Agnus castus fruit extract was safe and effective for relieving symptoms of premenstrual syndrome

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Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study.

OBJECTIVES To compare the efficacy and tolerability of agnus castus fruit (Vitex agnus castus L extract Ze 440) with placebo for women with the premenstrual syndrome. DESIGN Randomised, double blind, placebo controlled, parallel group comparison over three menstrual cycles. SETTING General medicine community clinics. PARTICIPANTS 178 women were screened and 170 were evaluated (active 86; ...

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Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder.

Clinical trials have demonstrated that serotonin reuptake inhibitors (SRIs) and the extract of Vitex agnus castus are effective for the treatment of premenstrual dysphoric disorder (PMDD). However, to the best of our knowledge, there has been no study comparing the efficacy of the SRIs with Vitex agnus castus (AC) extract. Therefore, the aim of the present study was to compare the efficacy of f...

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Antinociceptive and Anti-inflammatory Effects of Hydroalcohol Extract of Vitex agnus castus Fruit

In present study the effects of anti-inflammatory and antinociceptive of vitex hydro-alcoholic extract were evaluated on male mice. In inflammatory test mice were divided into 7 groups: first group was control. The second group, positive control group, received dexamethasone (15 mg/kg) and the other five groups received different doses of hydroalcohol extract of Vitex fruit (265, 365, 465, 565,...

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Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus.

A multicentric noninterventional trial (open study without control) to investigate the efficacy and tolerance of a drug in a large number of patients under routine medical conditions was performed for a new solid preparation from an extract of the fruit of Vitex agnus castus (VAC, Vitex, chaste tree, Chasteberry) in 1634 patients suffering from premenstrual syndrome (PMS). A specific questionna...

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Three new diterpenoids from the fruit of Vitex agnus-castus.

Three new labdane-type diterpenoids, viteagnusins F, G, and H, were isolated from the hexane extract of fruit (chasteberry) of Vitex agnus-castus L. (Verbenaceae) along with seven known compounds including four labdane-type diterpenoids, one norlabdane-type diterpenoid, one aromadendrane-type sesquiterpenoid, and one flavonoid. The chemical structures of the three new labdane-type diterpenoids ...

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ژورنال

عنوان ژورنال: Evidence-Based Mental Health

سال: 2001

ISSN: 1362-0347

DOI: 10.1136/ebmh.4.3.88